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1.

Oral Iptacopan Monotherapy in Paroxysmal Nocturnal Hemoglobinuria.

Peffault de Latour, Régis; Röth, Alexander; Kulasekararaj, Austin G; Han, Bing; Scheinberg, Phillip; Maciejewski, Jaroslaw P; Ueda, Yasutaka; de Castro, Carlos M; Di Bona, Eros; Fu, Rong; Zhang, Li; Griffin, Morag; Langemeijer, Saskia M C; Panse, Jens; Schrezenmeier, Hubert; Barcellini, Wilma; Mauad, Vitor A Q; Schafhausen, Philippe; Tavitian, Suzanne; Beggiato, Eloise; Chew, Lee Ping; Gaya, Anna; Huang, Wei-Han; Jang, Jun Ho; Kitawaki, Toshio; Kutlar, Abdullah; Notaro, Rosario; Pullarkat, Vinod; Schubert, Jörg; Terriou, Louis; Uchiyama, Michihiro; Wong Lee Lee, Lily; Yap, Eng-Soo; Sicre de Fontbrune, Flore; Marano, Luana; Alashkar, Ferras; Gandhi, Shreyans; Trikha, Roochi; Yang, Chen; Liu, Hui; Kelly, Richard J; Höchsmann, Britta; Kerloeguen, Cécile; Banerjee, Partha; Levitch, Rafael; Kumar, Rakesh; Wang, Zhixin; Thorburn, Christine; Maitra, Samopriyo; Li, Shujie.

N Engl J Med ; 390(11): 994-1008, 2024 Mar 14.

Artículo en Inglés | MEDLINE | ID: mdl-38477987

2.

Safety, tolerability, and activity of the active C1s antibody riliprubart in cold agglutinin disease: a phase 1b study.

D'Sa, Shirley; Vos, Josephine M I; Barcellini, Wilma; Wardecki, Marek; Perrin, Laurent; Barker, Graham; Zilberstein, Moshe; Storek, Michael; Chow, Timothy; Röth, Alexander.

Blood ; 143(8): 713-720, 2024 Feb 22.

Artículo en Inglés | MEDLINE | ID: mdl-38085846

3.

A role for codon order in translation dynamics.

Cannarozzi, Gina; Cannarrozzi, Gina; Schraudolph, Nicol N; Faty, Mahamadou; von Rohr, Peter; Friberg, Markus T; Roth, Alexander C; Gonnet, Pedro; Gonnet, Gaston; Barral, Yves.

Cell ; 141(2): 355-67, 2010 Apr 16.

Artículo en Inglés | MEDLINE | ID: mdl-20403329

4.

Sutimlimab in Cold Agglutinin Disease.

Röth, Alexander; Barcellini, Wilma; D'Sa, Shirley; Miyakawa, Yoshitaka; Broome, Catherine M; Michel, Marc; Kuter, David J; Jilma, Bernd; Tvedt, Tor H A; Fruebis, Joachim; Jiang, Xiaoyu; Lin, Stella; Reuter, Caroline; Morales-Arias, Jaime; Hobbs, William; Berentsen, Sigbjørn.

N Engl J Med ; 384(14): 1323-1334, 2021 04 08.

Artículo en Inglés | MEDLINE | ID: mdl-33826820

5.

Pegcetacoplan versus Eculizumab in Paroxysmal Nocturnal Hemoglobinuria.

Hillmen, Peter; Szer, Jeff; Weitz, Ilene; Röth, Alexander; Höchsmann, Britta; Panse, Jens; Usuki, Kensuke; Griffin, Morag; Kiladjian, Jean-Jacques; de Castro, Carlos; Nishimori, Hisakazu; Tan, Lisa; Hamdani, Mohamed; Deschatelets, Pascal; Francois, Cedric; Grossi, Federico; Ajayi, Temitayo; Risitano, Antonio; Peffault de la Tour, Régis.

N Engl J Med ; 384(11): 1028-1037, 2021 03 18.

Artículo en Inglés | MEDLINE | ID: mdl-33730455

6.

Sutimlimab in patients with cold agglutinin disease: results of the randomized placebo-controlled phase 3 CADENZA trial.

Röth, Alexander; Berentsen, Sigbjørn; Barcellini, Wilma; D'Sa, Shirley; Jilma, Bernd; Michel, Marc; Weitz, Ilene C; Yamaguchi, Masaki; Nishimura, Jun-Ichi; Vos, Josephine M I; Storek, Michael; Wong, Nancy; Patel, Parija; Jiang, Xiaoyu; Vagge, Deepthi S; Wardecki, Marek; Shafer, Frank; Lee, Michelle; Broome, Catherine M.

Blood ; 140(9): 980-991, 2022 09 01.

Artículo en Inglés | MEDLINE | ID: mdl-35687757

7.

Pegcetacoplan in paroxysmal nocturnal haemoglobinuria: Its use, its clinical effectiveness, and its influence on health-related quality of life and productivity.

Wilson, Koo; Rich, Carly; Hakimi, Zalmai; Horneff, Regina; Fishman, Jesse; Mellor, Jennifer; Earl, Lucy; Taylor, Yasmin; Simons, Alice; Conyers, Joe; Mulherin, Brian; Majerus, Elaine; Röth, Alexander.

Eur J Haematol ; 112(4): 516-529, 2024 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-37994576

8.

Fostamatinib for warm antibody autoimmune hemolytic anemia: Phase 3, randomized, double-blind, placebo-controlled, global study (FORWARD).

Kuter, David J; Piatek, Caroline; Röth, Alexander; Siddiqui, Asif; Numerof, Robert P; Dummer, Wolfgang.

Am J Hematol ; 99(1): 79-87, 2024 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-37929318

9.

COVID-19 vaccine safety and immunogenicity in patients with cold agglutinin disease receiving concomitant sutimlimab.

Fattizzo, Bruno; Röth, Alexander; Broome, Catherine M; Khan, Umer; Wardecki, Marek; Cordoba, Matias; Barcellini, Wilma.

Am J Hematol ; 99(4): 789-791, 2024 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-38385639

10.

Efficacy, Safety and Quality of Life of Pegcetacoplan in Japanese Patients With Paroxysmal Nocturnal Hemoglobinuria Treated Within the Phase 3 PEGASUS Trial.

Nishimori, Hisakazu; Nakazawa, Hideyuki; Tamura, Shinobu; Uchida, Toshiki; Usuki, Kensuke; Szamosi, Johan; de Latour, Régis Peffault; Röth, Alexander; Panse, Jens.

Acta Haematol ; 2024 Apr 12.

Artículo en Inglés | MEDLINE | ID: mdl-38615657

11.

Risk factors for thromboembolic events in patients with paroxysmal nocturnal hemoglobinuria (PNH): a nested case-control study in the International PNH Registry.

Höchsmann, Britta; Peffault de Latour, Regis; Hill, Anita; Röth, Alexander; Devos, Timothy; Patriquin, Christopher J; Chou, Wen-Chien; Jain, Deepak; Zu, Ke; Wu, Chuntao; Lee, Jong Wook.

Ann Hematol ; 102(11): 2979-2988, 2023 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-37668788

12.

Long-term outcomes of patients with paroxysmal nocturnal hemoglobinuria treated with eculizumab in a real-world setting.

Versmold, Katharina; Alashkar, Ferras; Raiser, Carina; Ofori-Asenso, Richard; Xu, Tao; Liu, Yutong; Katz, Pablo; Shang, Aijing; Röth, Alexander.

Eur J Haematol ; 111(1): 84-95, 2023 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-36971028

13.

Long-term effectiveness of eculizumab: Data from the International PNH Registry.

Terriou, Louis; Lee, Jong Wook; Forsyth, Cecily; Griffin, Morag; Szer, Jeff; Röth, Alexander; Gustovic, Philippe; Metzger, Jesse; Patel, Ami S; Patriquin, Christopher J.

Eur J Haematol ; 111(5): 796-804, 2023 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-37712908

14.

Sutimlimab provides clinically meaningful improvements in patient-reported outcomes in patients with cold agglutinin disease: Results from the randomised, placebo-controlled, Phase 3 CADENZA study.

Röth, Alexander; Broome, Catherine M; Barcellini, Wilma; Jilma, Bernd; Hill, Quentin A; Cella, David; Tvedt, Tor Henrik Anderson; Yamaguchi, Masaki; Lee, Michelle; Shafer, Frank; Wardecki, Marek; Jiang, Xiaoyu; Patel, Parija; Joly, Florence; Weitz, Ilene C.

Eur J Haematol ; 110(3): 280-288, 2023 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-36403132

15.

Crovalimab treatment in patients with paroxysmal nocturnal haemoglobinuria: Long-term results from the phase I/II COMPOSER trial.

Röth, Alexander; Ichikawa, Satoshi; Ito, Yoshikazu; Kim, Jin Seok; Nagy, Zsolt; Obara, Naoshi; Panse, Jens; Schrezenmeier, Hubert; Sica, Simona; Soret, Juliette; Usuki, Kensuke; Yoon, Sung-Soo; Balachandran, Nadiesh; Buri, Muriel; Lundberg, Pontus; Patel, Himika; Shinomiya, Kenji; Sostelly, Alexandre; Nishimura, Jun-Ichi.

Eur J Haematol ; 111(2): 300-310, 2023 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-37321625

16.

Sustained inhibition of complement C1s with sutimlimab over 2 years in patients with cold agglutinin disease.

Röth, Alexander; Barcellini, Wilma; D'Sa, Shirley; Miyakawa, Yoshitaka; Broome, Catherine M; Michel, Marc; Kuter, David J; Jilma, Bernd; Tvedt, Tor Henrik Anderson; Weitz, Ilene C; Yoo, Ronnie; Jayawardene, Deepthi; Vagge, Deepthi S; Kralova, Katarina; Shafer, Frank; WardÈ©cki, Marek; Lee, Michelle; Berentsen, Sigbjørn.

Am J Hematol ; 98(8): 1246-1253, 2023 08.

Artículo en Inglés | MEDLINE | ID: mdl-37246953

17.

Adamantylidenecarbene: Photochemical Generation, Trapping, and Theoretical Studies.

Roth, Alexander D; Wamsley, Christine E; Haynes, Sarah M; Thamattoor, Dasan M.

J Org Chem ; 88(20): 14413-14422, 2023 Oct 20.

Artículo en Inglés | MEDLINE | ID: mdl-37768172

18.

Carbenes from cyclopropanated aromatics.

Roth, Alexander D; Thamattoor, Dasan M.

Org Biomol Chem ; 21(48): 9482-9506, 2023 Dec 13.

Artículo en Inglés | MEDLINE | ID: mdl-37994575

19.

Declining Geographic Access to High-Volume Revision Total Hip Arthroplasty Surgeons: A National Medicare Analysis.

Jella, Tarun K; Manyak, Grigory A; Cwalina, Thomas B; Roth, Alexander L; Mesko, Nathan W; Kamath, Atul F.

J Arthroplasty ; 38(7 Suppl 2): S103-S110, 2023 07.

Artículo en Inglés | MEDLINE | ID: mdl-36634884

20.

Cup positioning and its effect on polyethylene wear of vitamin E- and non-vitamin E-supplemented liners in total hip arthroplasty: radiographic outcome at 5-year follow-up.

Baghdadi, Josef; Alkhateeb, Shareef; Roth, Alexander; Jäger, Marcus.

Arch Orthop Trauma Surg ; 143(3): 1679-1688, 2023 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-35397656

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